Description
Vessel system
| Item | Description |
| Vessel system | Glass vessel with rounded bottom and double jacket for temperature control Lid
volume:10L Design tank pressure: 0.1MPa Main material: 316L stainless steel top + borosilicate glass (acid, alkali, high temperature resistance); … 1… barg Sterilization temperature: 100-130 °C, sterilization time: 0-60min, maximum temperature: 135 °C Sterilization method: off-site sterilization There are three optional replenishment interfaces; Sampling and discharging interface 1 |
| Aeration system | Bottom ventilation (Air, O2,), surface ventilation (CO2, Air,N2), control interface can be selected in 1 way, Air and O2 ventilation ratio can be adjusted, bottom ring gas distributor, micro-bubble ventilation ring |
| Agitation system | Top magnetic coupling stirring system,infinite speed variation; rpm 20~200rpm±1rpm,The height of the stirring oar can be adjusted, |
| Temperature control | Electric heating, Culture temperature control range: Pt100 temperature display record control (0-150 °C), control accuracy: ±0.1°C, resolution: 0.1°C; |
| Air flow control | automatic control+manual control, mass meter display Each fermenter unit must have provision for working with 1 gase, namely, air,CO2 through mass flow controllers. 02 manual control, |
| Antifoam control | Automatically check foam, automatically add antifoam by peristaltic pump. |
| Feeding control | Control by peristaltic pump switch, automatically feeding and computation. |
| pH control | PID automatic control, carbon dioxide flow association automatic control
Peristaltic pump control, one-way control; Control range: 2-12pH, control accuracy: ±0.02pH, resolution: 0.01pH It has real-time curve and historical curve. |
| DO control | PID automatic control, Air and oxygen (according to DO level, automatically adjust the air and O2 ratio),
It can be controlled with the stirring speed, that is, by changing the stirring speed to adjust the dissolved oxygen; Display range: 0-150%, control range: 0-100% Display accuracy: ±1%, control accuracy: ±5%, resolution: 1% It has real-time curve and historical curve. |
| BLBIO-B Biology process controller | Control parameter: temp, pH, DO, antifoam, stirrer rev, feeding； |
| Control system | BLBIO B Control System: on-site controller, the next crew for the Siemens S7-1200 series PLC control system, it is a mature, stable, universal type of PLC, to suit a variety of automation applications, especially in manufacturing process control Application. Its modular, easy to implement distributed configuration and easy to master and so on, Siemens PLC control center has become a biological reaction process control implementation is economical and advanced control system, the system uses the touch screen display, on-site direct operations (menu type), all English menu and interface; also with the host computer for data transmission, data sampling and display tank, the system view of data analysis, reading settings.
12-inch LCD touch-sensitive screen as the display screen to display complete content-rich, user-friendly screen is simple, easy to operate. And disturbing each other. The control system can adapt to different range of sensors and actuators the output of the input signal with the signal anti-jamming system. Software: Siemens S7+ FORCE CONTORL Data collection and control module: Siemens S1200 PLC controller and data collection and control module 1. Control ① Manual control: You can set the percentage of open valve or a valve opening ② automatic control mode: You can select continuous or PID PID control the switch ③ sequence control: the control of all parameters can be pre-set at least 10 control section, ④ for automatic segmentation remotely control: PC control ⑤ acceptable correlation control: the dissolved oxygen can select speed, air flow rate, tank pressure, control of feeding, etc.; pH can choose to control with acid and alkali 2. Measurement function: can feeding, bubble enemy, such as measurement of pH 3. XY-axis to chart real progress can be any expansion and contraction of graphics display, to help the operator determine the parameters of the interaction between the effects of the fermentation process to quickly modify and adjust 4. Data Processing 1) to show that all the parameters of the trend curve analysis 2) to store, display, analyze all the historical curve parameters 3) can display all the parameters of the batch report 4) copy the data directly with the USB 5) data storage format is compatible with EXCEL, EXCEL platform can be to deal with 5. Controller self-protection function: to set the password, others can not modify the fermentation parameters; and the controller is not lost due to power settings for each parameter 6. Can the process control parameters, each parameter can have 10 block can be set 7. Time display of each parameter recording interval can be adjusted 8. Two parameters can be carried out with the screen settings and calibration 9. show the controller is really running against, the panel instructed the state process system, process hardware, and motion status indicator for understanding the various devices (such as peristaltic pumps, circulating pumps, heating, mixing, etc.) work status, Fault identification can be used as display 10. Each parameter of the transmission are independent modules, without disturbing each other, for easy maintenance 11.PH, DO and other parameters of control and associated controls can be adjusted |
Specification
| No | Parameter | Guideline | Controller data processing function |
| 1 | PH | Displaying range: 0.00~14.00±0.01
Auto-control range:2.00~12.00±0.05 Fermentation process control (According to the fermentation time, auto- control pH fluent, at least10 parts) |
pH value historical and trend curve analysis
Acid, alkali dosage curve analysis Batch report form analysis Acid, alkali total dosage record Keep and deliver data |
| 2
|
DO
|
0-150±3％，Displaying precision: 0.1％
It can be controlled by rev and feeding. Fermentation process control (According to the fermentation time, auto- control DO fluent, at least10 parts) |
DO value historical and trend curve analysis
Batch report form analysis Keep and deliver data |
| 3
|
Antifoam | Automatic PID control and alarm
Fermentation process control (According to the fermentation time, auto- control antifoam fluent, at least10 parts) |
Antifoam value historical and trend curve analysis
Foam error state record antifoam total dosage record Batch report form analysis Keep and deliver data |
| 4
|
Rev |
Automatic enactment and control（20~600rpm±1rpm）
Fermentation process control (According to the fermentation time, auto- control rev fluent, at least10 parts) |
Rev value historical and trend curve analysis
Batch report form analysis Keep and deliver data |
| 5 | Temperature | Temperature of cooling water: +5℃-60℃±0.2℃
Fermentation process control (According to the fermentation time, auto- control temperature fluent, at least10 parts) |
Temperature value historical and trend curve analysis
Batch report form analysis Keep and deliver data |
| 6
|
Feeding | PID automatic enactment and control
Fermentation process control (According to the fermentation time, auto- control feeding fluent, at least10 parts) |
Feeding value historical and trend curve analysis
Feeding total dosage record Batch report form analysis Keep and deliver data |
| 7 | Air flux | automatic control | 0.5vvm |
| 8
|
C02flux | automatic control | 0.1vvm |
| 9 | 02 flux | automatic control | 0.1vvm |
| 10 | N2 flux | automatic control | 0.1vvm |
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